NEW White Paper from Esco Documents Downflow Booth Surrogate Performance Test Results
Mar 08, 2010

Esco announces the publication of a NEW white paper that documents the Surrogate Performance Test Results of its Pharmacon(TM) Downflow Booths, per the Good Practice guidelines on Assessing the Particulate Containment Performance of Pharmaceutical Equipment published by the International Society for Pharmaceutical Engineering (ISPE).

A comprehensive battery of tests including filter integrity, downflow, bleed airflow, light intensity and noise level was carried out to verify the performance of the Esco Pharmacon Downflow booth. Booth performance was established to be within industry accepted and manufacturer’s criteria. A surrogate powder test involving the hand transfer of 25kg of lactose, in accordance with the ISPE Good Practice Guidelines, was then carried out. Multiple air sampling positions were strategically located at the operator breathing zone, inside, and outside the booth. Laboratory analysis of the sampling discs recovered indicated that booth performance was excellent, with all sampling locations, including the critical operator breathing zone, reading significantly less the industry-accepted criteria of 100 μg/m3.

For more details, download the white paper at the following address: http://www.escoglobal.com/resources/pdf/DFB_surrogate_powder_test.pdf.

Downflow Booths provide containment by utilizing high velocity air to capture airborne dust particles. Downflow Booths are versatile devices that can:• Be used to control exposure risk to hazardous materials for a wide variety of equipment and processes. • Enhance cGMP practices.

About Esco
Since 1978, Esco has emerged as a leader in the development of controlled environment, laboratory and cleanroom equipment solutions. Products sold in more than 100 countries include air showers, biological safety cabinets, downflow booths, ductless fume hoods, fan filter units, hospital pharmacy isolators, IVF workstations, lab animal research products, laboratory fume hoods, laboratory incubators, laboratory ovens, laminar flow cabinets, microplate shaker/incubators, modular cleanrooms, PCR cabinets, thermal cyclers and instrumentation, and powder weighing balance enclosures.